Check out these facts about CBD and diabetes to see how this plant can help. One of the most important ways that CBD possibly affects diabetes has These people also had higher levels of high-density lipoprotein cholesterol, as well as insulin resistance . Of every 10 of these dementia patients, six. But while some cholesterol is essential to life, too much can wreak havoc This can occur whether you have diabetes or not, but diabetes patients are at an like Cannabidiol (CBD), further suggests that medical marijuana. A quick Google search of the terms “CBD Oil” and “Diabetes” turns up million hits, with HDL cholesterol and other markers in 62 people with type 2 diabetes. a patient from seeking other therapies that have proven benefits.” Dr. Bhatia says that while CBD oil can have an important role to play in.
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Despite these interventions, diabetes is still the major cause of blindness, kidney failure, heart attacks and stroke, and is one of the leading causes of death worldwide. Therefore, it is crucial to have more treatment options available to patients to make sure their diabetes is well managed and controlled. Some find it helpful with controlling blood sugar, others find it useful for weight management, pain relief, depression or general wellbeing.
This has led to is considerable interest in how cannabis might affect diabetes, either positively or negatively, which has been investigated in a number of epidemiological the study and analysis of the patterns, causes, and effects of health and disease conditions studies. One US study suggested that current marijuana use was associated with lower insulin levels and greater insulin sensitivity both suggesting good blood sugar control in 4, participants. Another study showed that there was no association between marijuana use and diabetes in 3, participants, but there was a greater risk of pre-diabetes the stage before diabetes where higher than normal blood sugars are seen in a longitudinal study of participants.
Another longitudinal study of 17, participants in Sweden found no association between cannabis use and type 2 diabetes. Similarly, a smaller study 30 subjects found that cannabis smokers did not have different plasma levels of glucose or insulin. In fact a meta-analysis a study combining the statistics of several studies together suggested a possible protective effect of cannabis smoking in diabetes. The best way to prove that a medicine works is to test it in controlled clinical trials in the relevant patient population and to date, this has been investigation for cannabinoid-based medicines in diabetes in two areas: CBD combination drug licensed in Multiple Sclerosis.
Endocannabinoids were only discovered in the early s and since then we have learnt that the endocannabinoid system is an important set of chemical messengers, enzymes and receptors that control many bodily functions. One of these is the stimulation of appetite best known as the 'munchies' with cannabis smoking , and we know this is caused by activating the CB 1 receptor. Interestingly, rats lacking the CB 1 receptor by genetic modulation are protected from the development of obesity and type 2 diabetes, showing the importance of this receptor in regulating body weight and metabolism.
With this knowledge, a drug that blocks the CB 1 receptor called Rimonabant was developed by Sanofi with the theory that blocking the CB 1 receptor would reduce food intake and body weight. First licensed in , Rimonabant was an effective weight loss drug, and was also found to have positive effects in diabetic patients. Several large scale controlled clinical trials showed that Rimonabant improved blood sugar levels and the control of diabetes, associated with improvements in other metabolic parameters like cholesterol levels and waist circumference.
Despite these positive effects of the drug, Rimonabant was withdrawn from the market in because of safety concerns with side effects of depression and suicide ideation. However, the concept that blocking the CB 1 is beneficial in diabetes is still something being investigated. Drug companies and scientists are now looking at peripherally restricted drugs i. Pain is a long term complication of diabetes where patients develop nerve damage throughout the body called diabetic neuropathy, and this can be difficult to manage with conventional pain killers.
Since pain is a common reason that patients self-medicate with cannabis, some investigators have examined whether cannabinoids might be useful for this indication in diabetes. Best known is the case of Rick Simpson, who cured his basal cell carcinoma with cannabis oil and now has a widely distributed line of products.
Cannabis applied topically is not psychoactive. Cannabinoids have been proven to have an anti-inflammatory effect in numerous studies. CBD engages with the endocannabinoid system in many organs throughout the body, helping to reduce inflammation systemically. The therapeutic potential is impressively wide-ranging, as inflammation is involved in a broad spectrum of diseases. The oral use of cannabis and CBD for anxiety appears in a Vedic text dated around BCE, and it is one of the most common uses of the plant across various cultures.
While THC can increase anxiety in some patients, it lowers it in others. However, CBD effects have been shown to consistently reduce anxiety when present in higher concentrations in the cannabis plant. On its own, CBD has been shown in a number of animal and human studies to lessen anxiety. The stress-reducing effect appears to be related to activity in both the limbic and paralimbic brain areas.
A research review assessed a number of international studies and concluded that CBD has been shown to reduce anxiety , and in particular social anxiety, in multiple studies and called for more clinical trials.
It is suggested that patients work with a health care practitioner experienced in recommending cannabidiol or medicinal cannabis so that dosage and delivery methods can be developed and fine-tuned on an individual basis. At the same time, educated and aware patients can be their own highly informed health consultants.
For anxiety, CBD products with a ratio of High-CBD cannabinoids can be very effective in reducing chronic anxiety, treating temporary stress, and protecting the body from the physiological effects of both. Varieties high in linalool, a terpene shared with lavender, are known to be effective for relieving anxiety. Always start with the micro dose to test sensitivity and go up as needed within the dosing range, before going to the next, until symptoms subside.
The micro to standard dose is usually recommended to treat stress and anxiety with CBD. For relief of immediate symptoms, as in a panic or anxiety attack, vaporizing or smoking work well. The medication lasts one to three hours, whereas most ingested products, including CBD oil, take thirty to sixty minutes before taking effect and last six to eight hours.
Herbal vaporizers that use the whole plant are also an effective delivery method. Sublingual sprays or tinctures taken as liquid drops take effect quickly and last longer than inhaled products. The Cannabis Health Index CHI is an evidence-based scoring system for cannabis in general, not just CBD oil effects and its effectiveness on various health issues based on currently available research data.
Using this rubric and based on eleven studies, cannabis rated in the possible-to-probable range of efficacy for treatment of anxiety. Elixinol Organic High Potency CBD Capsules Elixinol offers a highly concentrated, high-potency, organic whole-hemp plant CBD oil , which is naturally extracted with carbon dioxide and free of all synthetics and chemicals. Whole-hemp plant extracts contain synergistic compounds that are believed to enhance the effectiveness and benefits of CBD. Clinical depression is a serious mood disorder characterized by persistent sadness and loss of interest, sometimes leading to decreased appetite and energy and suicidal thoughts.
Commonly used pharmaceuticals for depression often target serotonin, a chemical messenger that is believed to act as a mood stabilizer. The neural network of the endocannabinoid system works similarly to the way that serotonin, dopamine, and other systems do, and, according to some research, cannabinoids have an effect on serotonin levels. Whereas a low dose of THC increases serotonin, high doses cause a decrease that could worsen the condition.
CBD products with a ratio of Specifically, products made with Valentine X or Electra 4 are more energizing, helping relieve depression. When low energy is an issue, sativa or other stimulating strains can be helpful for improving energy and focus when THC can be tolerated. Varieties that are high in the terpene limonene are recommended for mood elevation. Always start with the micro dose to test sensitivity and go up as needed within the dosing range before going to the next, until symptoms subside.
The micro to standard dose is usually recommended to treat depression. Vaporized or smoked cannabis is recommended for relief of immediate symptoms, or a boost in dosage, and it can also be useful for sleep issues. The Cannabis Health Index CHI is an evidence-based scoring system for cannabis in general, not just CBD effects and its effectiveness on various health issues based on currently available research data.
Using this rubric and based on twenty-one studies, cannabis rated in the possible-to-probable range of efficacy for treatment of depression. Research in called for clinical trials to look into the effectiveness of cannabinoids for bipolar disorder manic depression.
It also works on the GABA-glutamate system and the hypothalamic-pituitary-adrenal axis. Its main role is restoring balance through inhibition when levels are too high and enhancement when they are too low. This is the most likely reason phytocannabinoids in general and CBD specifically are able to regulate depression and anxiety. The scientific inquiry into cannabis over the past several decades has confirmed that it is an effective and safe analgesic for many kinds of pain.
Of all the reasons that people use CBD today, pain is the most common. The same can be said of cannabis in general. In the United States, over seventy million people suffer from chronic pain, which is defined as experiencing over one hundred days per year of pain. Physicians differentiate between neuropathic usually chronic and nociceptive pains usually time-limited , and cannabis works on most neuropathic and many nociceptive types of pain.
A number of studies have demonstrated that the endocannabinoid system is both centrally and peripherally involved in the processing of pain signals. Cannabinoids can be used along with opioid medications, and a number of studies have demonstrated that they can reduce the amount of opioids needed, lessen the buildup of tolerance, and reduce the severity of withdrawal. It is suggested that patients work with a health care practitioner experienced in recommending CBD oil or medicinal cannabis so that dosage and delivery methods can be developed and fine-tuned on an individual basis.
Oral CBD products with a ratio of Most discussions of treating pain with CBD suggest that finding the right dosage is critical. Always start with the micro dose to test sensitivity and go up as needed within the dosing range by body weight until symptoms subside.
If CBD-dominant products alone are not enough to treat a particular case, products with a higher ratio of THC are sometimes recommended to better manage pain. This strain is a popular for patients who suffer from PTSD, epilepsy, cancer, multiple sclerosis, and autism. Although growers are striving to come up with even better CBD-rich strains, there has been suggestions that a completely no THC strain cannot exist because it plays a role in the plant structure.
The evidence can be seen in CBD-rich strains as the plants exhibit very weak stems and require many supports to hold up the plant until harvest. This stem weakness is much more severe in plants that have a lower THC content. After hearing that there are so many advantages to Cannabis, you may start to wonder if you need to smoke the herb in order receive the benefits. The answer is no. There are numerous ways in which individuals can be medicated without hitting a lighter.
Here are a list of ways Cannabis can be consumed: This is the most original and simple method of consuming Cannabis. The most common way is to grind up the dried female flower buds into fine granules, burn the content, and inhale the vaporized smoke containing the cannabinoids through a bong, pipe, paper-wrapped joint, and tobacco-leaf wrapped or cigar wrapping blunts.
For some individuals who want to intake less smoke, they may prefer smoking the Kief. Kief is a refined powder that contains the trichrome of the flower buds along with some leaves and flower residues. And when the residues are all sifted out, this super refined trichrome powder is called hash or hashish. Usually the hash is further processed into a sticky oil substance called wax it can also be called shatter, budder, honey oil, and butane hash oil depending on the appearance of the concentrate and the method being used to process the hash to be burned on the heating device or a vaping pen.
This wax is super high in THC and CBD content and should not be used by beginners as the dosage is very high compared to smoking or vaping. This method is commonly known as vaping. Like the nicotine vaporizers, the cannabinoids are extracted from the dried flowers into a concentrated oil often called hash oil through various methods.
This oil is then heated by the heating coil in the vaporizer pen or machine to about to F degrees and the oil is turned into a vapor for inhalation.
Cannabinoids can be extracted from the flower buds by using alcohol or food-grade glycerin to create a concentrated thick liquid solution. The most famous tincture is called Rick Simpson Oil that is originally produced from only indica strains of Cannabis to treat cancer and tumors. In last few years, rich CBD strains have also been processed into tincture so that children can benefit from the cannabinoids without needing to inhale vapor or eating an edible.
This method also allows a precise measurement of dosage for the treatment without any need of estimation. This category is quite similar to tincture. The only difference is that instead of using alcohol and food-grade glycerin to extract the cannabinoids, a fatty solvent is used for the extraction process.
The solvent can be butter, cocoa butter, coconut oil, various cooking oil such as olive oil, milk, cream, and even non-edible skin moisturizing oils. The food grade oil or cream infusions can then be eaten directly or made into an edible for consumption.
Those food items that include these oil infusions or tincture infusions are all categorized as edibles. These days, you can find anything a wide range of edibles that are similar to desserts and candy. Other edibles can include ice-cream, pasta sauce, coffee creamer, syrup, and even chewing gum. For individuals who do cannot ingest fat, dairy products, or alcohol due to various allergies or medical conditions, there are manufacture companies that have produced capsules that contain the extract for consumption.
Similar to nicotine patch, various manufacturer companies have produced a cannabinoid patch for individuals who just wish to enjoy the benefits without even consuming any Cannabis products. The cannabinoid-infused tampons is another variation from the same methods. Another variation works by an oral dissolve strip similar to a breath freshener strip.
According to the Drug Enforcement Agency in the United States, here are some of the possible short-term negative effects:. Other common symptoms of consuming Cannabis are dizziness, nausea, tiredness, and hallucinations. It is also important to note that Cannabis is not for everyone. Like any other medication treatments, each individuals show reactions that are slightly different from other people based on their allergies and physical condition.
Some people may exhibit allergy symptoms similar to pollen allergies since cannabinoids are extracted from the flower buds. In serious allergy cases, the individual may show swelling, excessive coughing, fever, and difficulty of breathing due to swelling of the air passages.
Individuals who are allergic or sensitive to smoke vapor should avoid smoking the cannabis. Because inhaling smoke can irritate the respiratory system, it should also be avoided by individuals who suffer from breathing-related conditions such as bronchitis and chronic obstructive pulmonary disease COPD. And as cannabinoids can produce a temporary increase in heart rate, individuals who suffer from high blood pressure or heart disease may want to avoid using cannabis unless they have consulted their doctors and have been advised otherwise.
Those who suffered from a stroke or heart attack must discuss the options with their doctors before trying any Cannabis products. Individuals who suffer from peripheral vascular disease caused by atherosclerosis should also avoid Cannabis because the elevated blood pressure may increase the chance of heart attacks, angina, and strokes.
Moreover, because Cannabis can cause dilation to the blood vessels, even the doctors do not know how the Cannabis will react with your medications.
Those individuals who are currently taking medications for their heart problems should also consult with their doctors to discuss whether Cannabis will interfere with their current medication. For those who are suffering from hepatitis C and other conditions related to liver damage should also refrain from consuming cannabinoids in high doses on a daily basis because it will cause furthermore liver complications.
Individuals who are suffering from various mental health conditions should also avoid using Cannabis. Although there has no direct correlation between mental illness and Cannabis use, there has been some research studies that indicate marijuana may exacerbate symptoms associated with psychosis or schizophrenia.
For those who wish to alleviate their mental illness conditions such as depression and bipolar disorder, these individuals should consult with their doctors about their options. Another important thing is that Cannabis is not for children or teenagers unless it is absolutely necessary for example, epilepsy and autism. While studies have shown that it does not pose as much damage as alcohol and many other illegal substances, there are still remaining questions about its possible influence on the developing brain.
What we do know is that the brain is under developing until early adulthood around the age of 25 years old. During this volatile stage, the increased cannabinoids can potentially interfere with the growth and development of the endocannabinoid system and neural pathways.
As a safety precaution, individuals should refrain from consuming Cannabis until they reach an age of 25 unless they have a medical condition that can benefit from the cannabinoids. Similarly, pregnant women should avoid consuming marijuana as they would for tobacco or alcohol. Any Cannabis use must be stopped before and during pregnancy as it can result in negative outcomes for both the mother and the baby. Although maternal use of Cannabis during pregnancy does not appear to be associated with low birth weight or early delivery, it may still affect the baby in the neural development that is related to the endocannabinoid system.
It has even been suggested that babies who were exposed to cannabinoids during the fetus phase has shown an attraction towards Cannabis in teenage and early adulthood. They are also shown to exhibit higher tolerance towards the herb. Unless there is an urgent medical need, the pregnant woman should not consume any Cannabis unless being advised by their physicians. Long-term side effects of Cannabis are still unclear in our current research on Cannabis consumption. A main concern includes cognitive and memory problems.
There has also been concern on children, teenagers, and young adults exposing to Cannabis may increase their chances of developing schizophrenia and various mental disorders such as anxiety disorder, bi-polar disorder, and depression. Even though the addictive properties of marijuana are relatively minimal compared to alcohol and other drugs, individuals who are prone to addictive behaviors may want to avoid cannabis because they may be more inclined to become dependent on the behavior.
Other long-term side effects may depends on the way Cannabis is consumed. One evident long-term side effect is that smoking marijuana can cause rapid aging of the skin. The THC smoke actually blocks the development of collagen from forming and causes your skin to age more quickly.
This problem can be avoided by using vaporizers, consuming edibles and other methods that do not include contact with the THC smoke. Similarly, smoking Cannabis is similar to smoking tobacco use; the smokes damages the lungs and increases the chance of lung complications and cancer.
The term chronic use can be confusing as there is no straight definition. According to science studies, chronic Cannabis smoking is defined by an average of 9 joints per day for a duration of at least 2 years. Those who self-report as a chronic Cannabis smoker are found to be associated with excessive abdominal fat and insulin resistance in the adipose tissues.
However, they do not suffer from fatty liver also known as hepatic steatosis , insulin insensitivity, glucose intolerance, or reduced pancreatic beta cell function. These findings are consistent with animal testing subjects. At the same time, clinical trials have found that heavy use of Cannabis can actually reduce body weight, diminish low high-density lipoprotein level, and decrease insulin resistance in human subjects.
Another important finding is that patients who suffer from chronic hepatitis C and use Cannabis on a daily basis are highly associated with hepatic steatosis.
There are actually evidence indicating that these patients may suffer from liver damage from chronic smoking of Cannabis.
This discovery suggests that individuals who suffer from diseases associated with liver problems should avoid Cannabis use unless necessary. There has been evidence that chronic Cannabis users has exhibit an elevated level of testosterones. This can lead to the development of acne and unusual hair loss. According to the United States Department of Health and Human Services, there were , emergency room visits that are associated with Cannabis use in This data does not mean that marijuana must be the direct cause of the visit.
It can mean that the individual has consumed marijuana before the emergency room visit. What is more important is that there has never been a case of marijuana overdose in history. As a matter of fact, medical studies have shown that Cannabis has a therapeutic index of 40, This index means that a person would need to take 40, times of the normal dosage in order to be overdosed morphine has a therapeutic index of Cannabis usually causes no tolerance or withdrawal symptoms except in chronic daily users.
Unlike alcohol, tobacco, various illegal drugs, Cannabis withdrawal symptoms is much more tame and likened to that of an individual trying to quit coffee. In a survey of heavy users, Those who enjoy using marijuana typically find it to be relaxing or mildly euphoric.
Some find it makes them more social or outgoing while other people claims that Cannabis makes them feel jittery, uncomfortable, tired, or remote.
New users often experience different effects than more experienced users. The number 1 mistake for new users is to consume too much in one go. This often leads to unpleasant feelings such as an increased heart rate, a sense of paranoia, cold sweat from the sudden adjustment of the sense impairment, and stinging of the throat especially individuals who have never smoke at all. As explained in earlier sections, there are many different strains of Cannabis.
Each strain of marijuana is different, varying in physical appearance and color, smell, and taste names are often associated with their special features; for example, the Skunk strains smells like Skunk, the Purple Urkle is named for its purplish hue color buds, and Pineapple Express smells like pineapples.
Inexperienced users should begin by consuming ONLY a small amount, such as one or two small puffs. Smoking and vaporizing have an immediate effect that can intensify quickly usually within minutes.
Instead of taking more puffs, wait at least minutes before using more. This way, you can gauge how 1 puff is affecting you. If you are vaping, keep in mind that the dosage is more potent in 1 puff. So go even slower. These are highly concentrated forms of Cannabis, such as hashes, kief, oils, and waxes, which are created by extracting cannabinoids from the flowers and leaves of Cannabis plants.
If you are comparing marijuana to alcohol, flowers is analogous to a light beer and concentrates to a hard liquor. If you are a beginner, never attempt to consume concentrates without being supervised. Even the experienced users can easily misjudge the dosage and find themselves stuck to the couch. If you are trying concentrates for the first time, begin with a VERY small amount and wait at least 30 minutes before taking another dose. It is essential to recognize that there are 2 important differences between consuming Cannabis via inhaling and ingesting:.
Here are some additional tips to keep in mind:. Remember that you should never feel pressured to try something that you do not feel safe or comfortable trying sometimes a store sales may push a new product on you for profit and know very little about your medical conditions.
The decision is up to you alone. Consuming too much Cannabis can be quite a very nasty experience. Anyone who has over-consumed marijuana edibles will tell you that not taking enough is far better than taking too much. Fortunately, marijuana is non-toxic to healthy human cells or organs. So you do not need to worry about dying from a Cannabis overdose. However, that does not mean you should not worry about over consumption.
Taking in too much marijuana in one sitting can make you instantly regret the decision, and it can happen with any type of Cannabis product if you are not careful. It is very important to remember that these symptoms are only temporary and will usually dispel within 15 minutes to an hour for smoked or vaporized Cannabis flowers, slightly longer for concentrates, and anywhere from 30 minutes to 2 hours for infused products and edibles.
If you know that you have overconsume or you are suspecting you have overconsumed, try to stay calm and remember that the feeling is only temporary.
Eating a bit of fatty food and drinking a lot of water can lessen the effect. Afterwards, lay or sit down, close your eyes, and try to relax. Keep your blood glucose testing kit close to you and check if necessary.
If you are with someone, let them know that you have over-consume Cannabis and ask them to keep an eye on you just as a safety pre-caution.
If your discomfort level becomes too unbearable that you think you need medical attention, ask someone to drive you to the emergency clinic or call for emergency help assistance. Do NOT try to drive anywhere by yourself! We hope that this article has provided you with helpful information on how Cannabis may be beneficial for individuals who are pre-diabetic, type 1 diabetic , or type 2 diabetic. It is important to remember that, like medication, Cannabis use should be limited to how much you actually need.
Obviously if you have too little, you may not see any benefits in the Cannabis consumption. With the right amount, you can get the greatest benefits.
Diabetes and Marijuana: A Possible Treatment?
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