EliteFitness.com Bodybuilding ForumsAdult male laboratory mice were exposed for 6 months to a combination of four anabolic-androgenic steroids primo cycles review the kinds and at the relative levels to which human athletes and body builders expose themselves. The four steroids included testosterone, two alkylated steroids, and an ester, and they do steroids shorten life span given at doses that totaled either 5 or 20 times normal androgenic maintenance levels for mice. Autopsy of the steroid-treated mice typically revealed tumors in the liver or kidney, other kinds of damage to these two organs, broadly do steroids shorten life span lymphosarcomas, or heart damage, and usually more than one of these conditions. It can be concluded that the life span of male mice is decreased dramatically by exposing them for 6 months to the kinds and relative levels of anabolic steroids used by many athletes and body builders. National Center for Biotechnology InformationU.
Exposure to anabolic-androgenic steroids shortens life span of male mice. - PubMed - NCBI
Athletes who are continuously using anabolic steroids are probably reducing their life expectancy. Biologists at the University of Texas draw this conclusion in an animal study published last century in Medicine and Science in Sports and Exercise. Anabolic steroids Before Franklin Bronson and Curt Matherne published their study in , researchers had only studied the health effects of anabolic steroids in animal studies that lasted a few weeks.
There had been no studies on the effects of extended use. Because the researchers realised that considerable numbers of athletes were continuously juicing for years on end, they decided to study the effect of steroids use over long periods in mice. Study The researchers gave male mice implants that continuously released testosterone, methyl testosterone, norethandrolone [structural formula shown on the right] and testosterone cypionate all anabolic steroids into the blood.
The mice were about two months old when they were fitted with the implants. In human terms they were young adults. The researchers kept the implants in the mice for 6 months, after which they removed them and then watched what happened to the mice in the following year.
The experiment lasted a total of 20 months. Lab mice can reach an age of about 26 months. So the experiment stopped when the mice, in human terms, were in their sixties. The researchers had divided the mice into three groups. One group was given implants that released no hormones [Control]. The third group of mice were given their steroids cocktail in a dose that was about four times that given to the Low Dose group. Results At the end of the experiment, 12 percent of the mice in the control group had died.
Of the mice that had been given a low dose of steroids, 33 percent had died. Of the mice that had been given a high dose of steroids, 52 percent had died. The researchers tried to establish the cause of death of all mice that had not made it to the equivalent of human retirement age. The picture that emerged, which is shown below, is pretty diverse. There was not one specific cause of death that stood out. The fatal liver tumours and cases of peliosis hepatitis were probably a consequence of the norethandrolone and methyl testosterone, the researchers wrote.
It is well known that alpha-alkyl steroids can cause liver damage, and most steroids users take this into account when designing their cycles. But even if you disregard these effects, the causes of death remain diverse. Adult male laboratory mice were exposed for 6 months to a combination of four anabolic-androgenic steroids of the kinds and at the relative levels to which human athletes and body builders expose themselves.
The four steroids included testosterone, two alkylated steroids, and an ester, and they were given at doses that totaled either 5 or 20 times normal androgenic maintenance levels for mice.
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